Gingival crevicular fluid as a source of biomarkers for periodontitis
نویسندگان
چکیده
منابع مشابه
Gingival Crevicular Fluid Biomarkers
Material and Method: Thirty patients were allocated into 3 groups: 10 were treated with scaling and root planing (SRP) only; 10 were treated with SRP and received adjunctive local metronidazole; 10 were treated with SRP and received adjunctive systemic metronidazole. Periodontal clinical parameters including plaque index, sulcus bleeding index, probing depth and relative attachment level were r...
متن کاملGingival Crevicular Fluid as a Novel Potential Source of Biomarkers Distinguishes Pubertal from Post-Pubertal Subjects
Detection of pubertal growth peak is vital in orthodontic treatment timing and planning. Gingival crevicular fluid (GCF) contains abundant proteins from different sources and has been proven to be an ideal source of biomarkers. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) is an advanced technique that can detect low-molecular-weight peptides with h...
متن کاملDiagnostic accuracy for apical and chronic periodontitis biomarkers in gingival crevicular fluid: an exploratory study.
AIM The aim of this study was to assess the levels and diagnostic accuracy of a set of potential biomarkers of periodontal tissue metabolism in gingival crevicular fluid (GCF) from patients with chronic periodontitis (CP) and asymptomatic apical periodontitis ( AAP). MATERIALS AND METHODS Thirty one GCF samples from 11 CP patients, 44 GCF samples from 38 AAP patients and 31 GCF samples from 1...
متن کاملSubantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women.
BACKGROUND We recently demonstrated that a 2-year subantimicrobial-dose doxycycline (SDD) regimen (double-masked, placebo-controlled clinical trial) in postmenopausal (PM) women exhibiting mild systemic bone loss (osteopenia) and local bone loss (periodontitis) reduced the progression of periodontal attachment loss (intent-to-treat analysis) and the severity of gingival inflammation and alveola...
متن کاملGingival Crevicular Fluid Immunoglobulins in Smokers with Chronic Periodontitis
Tobacco smoking is regarded as one of the most significant risk factors in the development and progression of periodontal disease. Studies have shown an altered host antibody response to antigenic challenge in smokers with periodontitis. The study was undertaken to estimate the gingival crevicular fluid (GCF) immunoglobulin G,A,M (IgA, IgG and IgM) levels in smokers and non smoker with periodon...
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ژورنال
عنوان ژورنال: Periodontology 2000
سال: 2015
ISSN: 0906-6713
DOI: 10.1111/prd.12107